Which organism is NOT typically associated with gastrointestinal disease?

Toxoplasma gondii is primarily associated with a disease known as toxoplasmosis, which usually presents with flu-like symptoms, ocular issues, and in some cases, severe complications in immunocompromised individuals and during pregnancy. While it can be transmitted through food, particularly undercooked meat or contaminated water, its primary impact is not on the gastrointestinal system, distinguishing it from other organisms listed, which are more directly associated with intestinal infections.

In contrast, Giardia lamblia, Entamoeba histolytica, and Ascaris lumbricoides are well-known for causing gastrointestinal diseases. Giardia lamblia is a protozoan that leads to giardiasis, presenting with diarrhea and abdominal pain. Entamoeba histolytica can cause amoebic dysentery, which results in severe diarrhea and intestinal ulceration. Ascaris lumbricoides, a helminth, can lead to ascariasis, with symptoms resulting from intestinal blockage and malnutrition.

In summary, Toxoplasma gondii's association with non-gastrointestinal conditions makes it the organism that is not typically linked to gastrointestinal disease.